
In February 2016, after more than a decade of worsening memory loss that neurologists had attributed to early-onset Alzheimer’s disease and depression, 79-year-old Kris Kristofferson underwent blood testing ordered after his cardiologist and his wife, Lisa Meyers, looked past the existing diagnoses.
When the laboratory results returned positive for Lyme disease, Meyers traced the likely infection back to 2005, when Kristofferson had spent six weeks crawling across the forest floor in Northeast Kingdom, Vermont, filming the independent drama Disappearances. For years afterward, he had taken prescribed medications for Alzheimer’s, fibromyalgia, and clinical depression while his short-term recall continued to slip away.
Once specialists took him off the Alzheimer’s drugs and placed him on targeted Lyme treatments in early 2016, his mental clarity returned within weeks. That medical reversal was the latest chapter in a partnership that had begun thirty-four years earlier in Malibu, California, when Kristofferson’s life and career were near collapse.
By 1982, the former Rhodes Scholar, Army helicopter pilot, and songwriter had gone through two divorces, including his publicized 1980 split from singer Rita Coolidge. His leading-man film career had stalled following the box-office disaster of Michael Cimino’s 1980 Western Heaven’s Gate, and doctors had warned him that his heavy drinking was damaging his liver.
That year, the 46-year-old singer walked into a Malibu gym and met Meyers, a 26-year-old law student at Pepperdine University. Unlike the musicians and actors who had surrounded him in Los Angeles and Nashville, Meyers was studying contract law and had little interest in the Hollywood social circuit.
The couple married on February 18, 1983, inside the chapel at Pepperdine University in Malibu. After finishing her legal studies, Meyers stepped in to help manage his business affairs, untangling decades of touring schedules and publishing commitments while encouraging him to leave the Los Angeles nightlife behind.
With order restored to his schedule, Kristofferson returned to recording in 1985 alongside close friends Johnny Cash, Waylon Jennings, and Willie Nelson as The Highwaymen. Rather than raising their growing family in Southern California, Kristofferson and Meyers bought land near Hamoa Beach in the remote eastern town of Hana on the island of Maui, Hawaii.
Reachable primarily by the narrow, winding Hana Highway, the oceanfront property gave the couple 180 degrees of open Pacific horizon and almost no immediate neighbors. Over the next decade, they raised five children together on the island—Jesse Turner, born in October 1983, followed by Jody Ray, Johnny Robert, Kelly Marie, and Blake Cameron—while staying connected to Kristofferson’s three older children, Tracy, Kris, and Casey.
In Hana, the man who had written standards for Janis Joplin, Johnny Cash, and Ray Price spent his days off the road clearing brush and mowing acres of coastal grass on his John Deere tractor. He and Meyers became quiet fixtures in the rural district, donating computers to Hana High and Elementary School and supporting local environmental efforts.
That daily routine on Maui made it obvious to Meyers when her husband began forgetting lyrics and losing track of conversations only moments after they ended. Refusing to accept that his decline was irreversible dementia, she accompanied him from specialist to specialist until the 2016 blood panels revealed the tick-borne infection.
With his memory stabilized after treatment, Kristofferson returned to the stage for four more years of international touring. Teaming up with Merle Haggard’s longtime backing band, The Strangers, he played packed theaters across North America and Europe, including a return to the Glastonbury Festival in 2017 at age 81.
He gave his final full concert on January 30, 2020, aboard the Norwegian Pearl during the Outlaw Country Cruise, closing the twenty-song set alongside The Strangers before quietly retiring to Maui the following year.
In April 2023, Lisa accompanied him to the Hollywood Bowl for Willie Nelson’s 90th birthday concerts, where Kristofferson walked onstage to sing one more duet with Rosanne Cash.
Seventeen months later, on September 28, 2024, Kristofferson died at age 88 at the house in Hana overlooking the Pacific, with Lisa and his children gathered in the home where she had protected his health and peace for forty-one years. For a quick look at how his medical turnaround unfolded, watch Kris Kristofferson: The Misdiagnosis That Gave Him Precious Time Back, which highlights how uncovering his Lyme disease restored his final years with his family.